Copied!

Pathway Search



alanine metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
1,3-diaminopropane + H2O + O2 <=> 3-aminopropionaldehyde + NH3 + H2O2 1.4.3.10 putrescine oxidase
1.4.3.21 primary-amine oxidase
1.4.3.22 diamine oxidase



N-Carbamoyl-beta-alanine + H2O + H+ <=> beta-Alanine + NH3 + CO2 3.5.1.6 beta-ureidopropionase

ATP + L-alanine + tRNAMet <=> AMP + diphosphate + L-alanyl-tRNA 6.1.1.15 proline---tRNA ligase
6.1.1.20 phenylalanine---tRNA ligase
6.1.1.6 lysine---tRNA ligase
6.1.1.7 alanine---tRNA ligase




a_D-amino_acid + H2O + a_quinone <=> a_2-oxo_carboxylate + NH3 + a_quinol 1.4.5.1 D-amino acid dehydrogenase (quinone)

3-aminopropionaldehyde + NADP+ + H2O <=> beta-Alanine + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase


D-lactate + NAD+ <=> pyruvate + NADH + H+ 1.1.1.27 L-lactate dehydrogenase
1.1.1.28 D-lactate dehydrogenase
1.1.1.345 D-2-hydroxyacid dehydrogenase (NAD+)



4-Aminobutyraldehyde + NAD+ + H2O <=> 4-aminobutanoate + NADH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase







3-hydroxypropionate + NAD+ <=> malonate_semialdehyde + NADH + H+ 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
1.1.1.31 3-hydroxyisobutyrate dehydrogenase
1.1.1.59 3-hydroxypropionate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase




L-valine + 2-oxoglutarate <=> L-glutamate + 2-oxoisovalerate 2.6.1.39 2-aminoadipate transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.6 leucine transaminase
2.6.1.66 valine---pyruvate transaminase




acetyl-CoA + propionate <=> acetate + propionyl-CoA 2.8.3.1 propionate CoA-transferase
2.8.3.12 glutaconate CoA-transferase
2.8.3.14 5-hydroxypentanoate CoA-transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase




pyruvate + L-valine <=> L-alanine + 2-oxoisovalerate 2.6.1.12 alanine---oxo-acid transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.51 serine---pyruvate transaminase
2.6.1.66 valine---pyruvate transaminase




L-cysteine + [enzyme]-cysteine <=> L-alanine + [enzyme]-S-sulfanylcysteine 2.8.1.7 cysteine desulfurase

O2 + H2O + D-Aspartate <=> NH3 + H2O2 + oxaloacetate 1.4.3.1 D-aspartate oxidase
1.4.3.15 D-glutamate(D-aspartate) oxidase
1.4.3.3 D-amino-acid oxidase



CoA + propionate + ATP <=> propionyl-CoA + diphosphate + AMP 6.2.1.1 acetate---CoA ligase
6.2.1.17 propionate---CoA ligase
6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.30 phenylacetate---CoA ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
6.2.1.44 3-(methylthio)propionyl---CoA ligase






propionyl-CoA + D-lactate <=> propionate + (R)-lactoyl-CoA 2.8.3.1 propionate CoA-transferase

(R)-lactoyl-CoA <=> H2O + acryloyl-CoA 4.2.1.54 lactoyl-CoA dehydratase

malonate_semialdehyde + L-alanine <=> beta-Alanine + pyruvate 2.6.1.113 putrescine---pyruvate transaminase
2.6.1.18 beta-alanine---pyruvate transaminase
2.6.1.2 alanine transaminase
2.6.1.40 (R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.77 taurine---pyruvate aminotransferase





propionyl-CoA + NAD+ <=> acryloyl-CoA + NADH + H+ 1.3.1.84 acrylyl-CoA reductase (NADPH)
1.3.1.95 acrylyl-CoA reductase (NADH)


2-oxoglutarate + L-alanine <=> L-glutamate + pyruvate 2.6.1.1 aspartate transaminase
2.6.1.12 alanine---oxo-acid transaminase
2.6.1.2 alanine transaminase
2.6.1.37 2-aminoethylphosphonate---pyruvate transaminase
2.6.1.39 2-aminoadipate transaminase
2.6.1.4 glycine transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.5 tyrosine transaminase
2.6.1.79 glutamate---prephenate aminotransferase









L-aspartate <=> D-Aspartate 5.1.1.10 amino-acid racemase
5.1.1.13 aspartate racemase


pyruvate + D-methionine <=> L-alanine + 4-methylsulfanyl-2-oxobutanoate 2.6.1.21 D-amino-acid transaminase
2.6.1.41 D-methionine---pyruvate transaminase


5,6-dihydrouracil + NADP+ <=> Uracil + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)


L-alanine + H2O + NAD+ <=> pyruvate + NH3 + NADH + H+ 1.4.1.1 alanine dehydrogenase
1.4.1.23 valine dehydrogenase (NAD+)
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.8 valine dehydrogenase (NADP+)
1.4.1.9 leucine dehydrogenase





spermidine + H2O + acceptor <=> 1,3-diaminopropane + 4-Aminobutyraldehyde + reduced_acceptor 1.4.9.1 methylamine dehydrogenase (amicyanin)
1.5.99.6 spermidine dehydrogenase


H+ + L-aspartate <=> beta-Alanine + CO2 4.1.1.11 aspartate 1-decarboxylase
4.1.1.15 glutamate decarboxylase
4.1.1.25 tyrosine decarboxylase
4.1.1.29 sulfinoalanine decarboxylase




2-oxoglutarate + D-alanine <=> D-glutamate + pyruvate 2.6.1.2 alanine transaminase
2.6.1.21 D-amino-acid transaminase


L-alanine <=> D-alanine 2.6.1.21 D-amino-acid transaminase
5.1.1.1 alanine racemase
5.1.1.10 amino-acid racemase
5.1.1.12 ornithine racemase
5.1.1.13 aspartate racemase
5.1.1.15 2-aminohexano-6-lactam racemase
5.1.1.18 serine racemase
5.1.1.8 4-hydroxyproline epimerase
5.1.1.9 arginine racemase









NAD+ + H2O + L-glutamate <=> NADH + 2-oxoglutarate + NH3 + H+ 1.4.1.14 glutamate synthase (NADH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
1.4.1.5 L-amino-acid dehydrogenase





L-aspartate + H+ <=> L-alanine + CO2 4.1.1.12 aspartate 4-decarboxylase
4.4.1.1 cystathionine gamma-lyase


bithionol <=> acryloyl-CoA + H2O 4.2.1
4.2.1.116 3-hydroxypropionyl-CoA dehydratase
4.2.1.17 enoyl-CoA hydratase



spermine + O2 + H2O <=> spermidine + 3-aminopropionaldehyde + H2O2 1.5.3.16 spermine oxidase
1.5.3.17 non-specific polyamine oxidase


beta-Alanine + 2-oxoglutarate <=> malonate_semialdehyde + L-glutamate 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2 alanine transaminase
2.6.1.22 (S)-3-amino-2-methylpropionate transaminase
2.6.1.55 taurine---2-oxoglutarate transaminase
2.6.1.ak





H2O + 5,6-dihydrouracil <=> H+ + N-Carbamoyl-beta-alanine 3.5.2.16 maleimide hydrolase
3.5.2.2 dihydropyrimidinase


(S)-malate + NAD+ <=> oxaloacetate + NADH + H+ 1.1.1.28 D-lactate dehydrogenase
1.1.1.299 malate dehydrogenase [NAD(P)+]
1.1.1.337 L-2-hydroxycarboxylate dehydrogenase (NAD+)
1.1.1.37 malate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.81 hydroxypyruvate reductase
1.1.1.82 malate dehydrogenase (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase
1.1.1.95 phosphoglycerate dehydrogenase
1.1.1.96 diiodophenylpyruvate reductase











Visualization of the pathway